Puberty timing associated with obesity and central obesity in Chinese Han girls
نویسندگان
چکیده
منابع مشابه
Variants in the fat mass- and obesity-associated (FTO) gene are not associated with obesity in a Chinese Han population.
OBJECTIVE Recently, genome-wide association studies have provided evidence that several common variants within the fat mass-and obesity-associated (FTO) gene were significantly associated with obesity in populations of European origin. However, their effects in other ethnic populations remain to be elucidated. RESEARCH DESIGN AND METHODS In this study, we examined the association between thre...
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Precocious puberty can cause several adverse effects on final growth and social behavior in girls. Recently studies showed that low serum vitamin D levels might be associated with precocious puberty. The aim of this research was to investigate the association between serum vitamin D levels and central precocious puberty in girls. Girls with central precocious puberty under the age of 8 we...
متن کاملHigher prevalence of obesity and overweight without an adverse metabolic profile in girls with central precocious puberty compared to girls with early puberty, regardless of GnRH analogue treatment
OBJECTIVES 1. To determine BMI, obesity/overweight rates, glucose and lipids at baseline, during GnRHa treatment and shortly after therapy discontinuation in female children with CPP and EP. 2. To compare this response to that seen in a similar group of untreated patients. METHODS A retrospective analysis of 71 children with either CPP (n = 37) or EP (n = 34) was undertaken. Forty three were ...
متن کاملLIN28B polymorphisms are associated with central precocious puberty and early puberty in girls
PURPOSE Single-nucleotide polymorphism (SNP) markers within LIN28B have been reported to be related to the timing of pubertal growth. However, no study has investigated the frequency of genetic markers in girls with precocious puberty (PP) or early puberty (EP). This study aimed to determine the frequency of putative genetic markers in girls with PP or EP. METHODS Genomic DNAs were obtained f...
متن کاملCommon rs7138803 variant of FAIM2 and obesity in Han Chinese
BACKGROUND Obesity causes severe healthcare problem worldwide leading to numerous diseases, such as cardiovascular diseases and diabetes mellitus. Previous Genome-Wide Association Study (GWAS) identified an association between a single nucleotide polymorphism (SNP) rs7138803, on chromosome 12q13 and obesity in European Caucasians. Since the genetic architecture governing the obesity may vary am...
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ژورنال
عنوان ژورنال: BMC Pediatrics
سال: 2019
ISSN: 1471-2431
DOI: 10.1186/s12887-018-1376-4